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Levothyroxine, also L-thyroxine or T4, is a artificial form of the thyroid hormone thyroxine, which is normally secreted near thefollicular cells of the thyroid gland. It is also toughened to use thyroid hormone deficiency, and off to abort the recurrence of thyroid cancer. Like its simply secreted counterpart, levothyroxine is chemically in the chiral L-form. The allied cure dextrothyroxine (D-thyroxine) was habituated to in the past as a treatment as a replacement for hypercholesterolemia (happy cholesterol levels) but was reticent fitting to cardiac side-effects.
Biography
Thyroxine was sooner individual in disinfected form in 1914 at the Mayo Clinic past Edward Calvin Kendall from extracts of hog thyroid glands.[3 - The hormone was synthesised in 1927 aside British chemists Charles Robert Harington and George Barger.
Medical uses
Levothyroxine is typically adapted to to premium hypothyroidism.[4 - It may also be used to go into goiter via its talent to lower thyroid-stimulating hormone (TSH), a hormone that is considered goiter-inducing.[5 - [6 - In 1992, President George H.W. Bush told box pack Larry Monarch that he had been prescribed levothyroxine as instances partly of a treatment regimen as a service to Graves' condition; the interchange was disseminate live to follower dish owners tracking and recording backhaul channels.[7 -
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